International Journal of Stroke: Podcast Series
Health & Fitness:Medicine
Dr George Ntaois on 'Oral anticoagulation versus antiplatelet/placebo for stroke prevention in patients with heart failure and sinus rhythm: systematic review and meta-analysis of randomized controlled trials'
Previous meta-analyses of randomized controlled trials of oral anticoagulation in patients with heart failure and sinus rhythm reported reduced stroke risk and increased bleeding risk compared to antiplatelets or placebo. However, the effect estimates may be subject to imprecision, as all included trials were prematurely terminated, stroke was not the primary outcome and overall results were primarily driven by a single trial which accounted for >80% of all strokes. Current guidelines do not provide strong recommendations about the role of oral anticoagulants in heart failure patients with sinus rhythm.
Carmen Lahiff-Jenkins, Managing Editor of the International Journal of Stroke and I spoke to George Ntaios the Department of Medicine, University of Thessaly, Larissa, Greece.
Dr Ntaios and his team wanted to provide a more accurate estimate of the effect of oral anticoagulation on stroke risk in heart failure patients with sinus rhythm by systematic review and meta-analysis of available randomized controlled trials including the recently published evidence.
Link to article here
Music by Kevin McLeod
Mark Boulos IJS Canadian Stroke Congress
Mitchell Elkind IJS and Canadian Stroke Congress
ICARUSS - Jacques Joubert
Tim Klienig
Christopher Levi
Anne Alexandrov
Richard Lindley and Mohammad Alim
Leeanne Carey
Caroline Watkins
Dominique Cadilhac
Eng Lo
Improved ischemic stroke outcome prediction using model estimation of outcome probability: the THRIVE-c calculation’ - Alexander Flint
What’s New in Stroke? Phase III Randomized Clinical Trials of 2012-2014 - Robert Hart
World Stroke Organization Stroke Research Committee - Ralph Sacco
Safeguarding the safety of stroke patients: credentialing of neurointerventionists for mechanical thrombectomy - Bernard Yan
Endovascular Stroke Therapy – a new era - Michael Hill and Mayank Goyal
Stroke in Bahrain: rising incidence, multiple risk factors, and sub-optimal care, published in Volume 10 Issue 4, June 2015 International Journal of Stroke
Burden of stroke in Italy: an economic model highlights savings arising from reduced disability following thrombolysis
World Stroke Organization Guidelines
Should minor stroke patients be thrombolysed? A focused review and future directions
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