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About This Episode:
The Sydney Diet-Heart Study was a clinical trial conducted in the 1960s and 1970s that aimed to examine the hypothesis that reducing saturated fat intake in the diet would lead to a reduced risk of heart disease.
However, it really only gained attention after a more recent re-analysis by Ramsden et al., which in recent years has been used as supporting evidence for the idea that increased polyunsaturated fat (PUFA), and specifically linoleic acid, in addition to reduced saturated fat intake, can increase heart disease risk.
This was based on the findings that substituting linoleic acid in place of saturated fat increased all-cause, CVD and CHD mortality.
This is of course counter to prevailing consensus and guidelines in this area, which routinely show reduced risk on replacing SFA with PUFA.
Could this trial undermine the common conclusions that replacing saturated fat with polyunsaturated fat decreases heart disease risk?
In this episode Alan and Danny discuss some of the crucial aspects to understand about this study and what it means for what conclusions can be made about the impact of PUFA broadly, and linoleic acid specifically, on our health.
#288: Ted Ryce: Meditation, Communication & Understanding Behaviours
#287: Gregg Slater - Dietary Fatigue, Nutrition Periodization & the Deficit-Adherence Model
#286: James Morton, PhD - Fuelling Elite Sport: Team Sky, Liverpool FC & Carbohydrate Periodization
#285: What is Health? A Conceptual Framework
#284: Simone Harding – Tackling Negative Body Image & Weight Stigma
#283: Alun Williams, PhD - The Genetics & Science Behind the Historic Caster Semenya/IAAF Case
#282: Louise Burke, PhD - Project Supernova: The Science of Fuelling Elite Athletes
#281: Jake Linardon, PhD – Eating Disorders, Binge Eating & Body Image
#280: Kirsty Elliot-Sale, PhD – Energy Availability, Menstrual Disorders & RED-S
#279: Avrum Bluming, MD & Carol Tavris, PhD – Estrogen, Menopause & Misconceptions About Hormone Replacement
#278: Jackson Peos, PhD – The ICECAP Trial, Intermittent Energy Restriction & the Science of Diet Breaks
#277: Eric Helms, PhD - Non-Quantitative Dieting, Personal Experiments & Optimal Weight Gain for Hypertrophy
#276: Nick Gant, PhD - Neurometabolism: Brain Function, Fatigue & Nutritient Interventions
#275: Kate Solovieva - Psychology, Empathy & Coping Strategies for Better Coaching
#274: James Lindsay, PhD - When Peer-Review Goes Wrong
#273: Bryan Chung, MD, PhD – Dealing with Science Overwhelm & Improving Your Relationship with Research
#272: Barbora de Courten, PhD – Effect of Carnosine on Glucose Metabolism and Chronic Disease Risk
#271: Prof. John Hawley – Circadian Metabolomics & Time-Restricted Feeding
#270: Alexander Kolliari-Turner – Anabolic Steroids, Muscle Memory & Advances in Drug Testing
#269: Lyndon Purcell & Jacob Schepis: Physiology, Hypertrophy & Discussions
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