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About This Episode:
The Sydney Diet-Heart Study was a clinical trial conducted in the 1960s and 1970s that aimed to examine the hypothesis that reducing saturated fat intake in the diet would lead to a reduced risk of heart disease.
However, it really only gained attention after a more recent re-analysis by Ramsden et al., which in recent years has been used as supporting evidence for the idea that increased polyunsaturated fat (PUFA), and specifically linoleic acid, in addition to reduced saturated fat intake, can increase heart disease risk.
This was based on the findings that substituting linoleic acid in place of saturated fat increased all-cause, CVD and CHD mortality.
This is of course counter to prevailing consensus and guidelines in this area, which routinely show reduced risk on replacing SFA with PUFA.
Could this trial undermine the common conclusions that replacing saturated fat with polyunsaturated fat decreases heart disease risk?
In this episode Alan and Danny discuss some of the crucial aspects to understand about this study and what it means for what conclusions can be made about the impact of PUFA broadly, and linoleic acid specifically, on our health.
SNR #125: Cassandra Forsythe PhD, RD - Amenorrhea, Cellulite & Low FODMAP Diets for IBS
#124: Brent Ruby, PhD - The Human Ceiling of Energy Expenditure
SNR #123: Donald Layman, PhD - Leucine Kinetics, mTOR Activation & the Anabolic Response to Protein
SNR #122: Brett Gibbs - Powerlifting Meet Preparation, Making Weight & Insights into a World Champion Mindset
SNR #121: Graeme Close, PhD - Nutritional Strategies for Jockeys to Make Weight, Perform Better & Improve Health
SNR #120: Kevin Folta, PhD - An Evidence-Based View of Genetically Modified Foods
SNR #119 - Krista Casazza, PhD - Obesity Myths, Epigenetics of Obesity & Role of Muscle in Weight Loss
SNR #118 - Caoileann Murphy, PhD - Protein Distribution, Per Meal Dosing & Muscle Protein Balance
SNR #117: Prof. Julia Rucklidge - Role of Micronutrients in Mental Health & Psychiatric Disorders
SNR #116: Prof. Kevin Tipton - Nutritional Support for Injuries, Protein Metabolism & Optimal Protein Distribution
SNR #115: Dr. Quinn Henoch – Physical Therapy for Athletes, Movement Screening & Addressing “Butt Wink”
SNR #114: Ryan Doris – Adapting to Succeed, Self-Responsibility for Failure & What Being Elite Means
SNR #113: One Thing To Improve Your Life
SNR #112: The Best Way To Be Wrong
SNR #111: Grace Liu, PhD - Probiotics, Fiber & Creating a Healthy Gut
SNR #110: Nanci Guest, RD - Nutrigenomics in Health & Athletic Performance
SNR #109: Ben Esgro, RD - Physiology, Abuse of Science & Silver Bullet Theory
SNR #108: Your Mentality Towards Nutrition - Lessons From Eric Helms
SNR #107: Brad Dieter, PhD - Science Driven Nutrition & Putting Research in Context
SNR #106: Rick Miller, RD - The Role of Beta-Casein Proteins in Digestion & Health
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