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About This Episode:
The Lyon Diet Heart Study (LDHS) is often cited as one of the pivotal studies that helped establish the Mediterranean diet as a recognized and recommended dietary pattern for cardiovascular health.
A clinical trial conducted in Lyon, France, the LDHS showed significant reduction in cardiac death could be achieved in secondary prevention patients using a dietary intervention.
Conducted between 1992 to 1996, the study involved 605 participants who had previously experienced a heart attack (myocardial infarction).
LDHS showed an incredible 75% lower risk of cardiac death in these patients. This remarkable reduction was unexpected and led to considerable attention from the medical and scientific communities.
LDHS is interesting to dig into for several reasons. First, it’s clever methodology was able to account for some challenges of doing nutrition research. Second, the dietary intervention, whilst named as a “Mediterranean diet”, should perhaps be considered differently.
In this episode, Alan and Danny dig into all the details, highlighting some important lessons we can take from LDHS.
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#272: Barbora de Courten, PhD – Effect of Carnosine on Glucose Metabolism and Chronic Disease Risk
#271: Prof. John Hawley – Circadian Metabolomics & Time-Restricted Feeding
#270: Alexander Kolliari-Turner – Anabolic Steroids, Muscle Memory & Advances in Drug Testing
#269: Lyndon Purcell & Jacob Schepis: Physiology, Hypertrophy & Discussions
#268: Luke Leaman - Physiology, Nutrition From First Principles & Prioritising Health
#267: Fiona Willer, AdvAPD - Health At Every Size, Non-Dieting & Weight-Neutral Approaches
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#265: Lessons From Experts - Prediabetes, Autophagy, Relative Energy Deficiency and Carbohydrate Periodization
#264: Prof. Michael Ristow – Longevity, Mitochondria & Free Radicals
#263: Brenda Davy, PhD – Dietary Assessement Methods in Nutrition Research
#262: Trevor Kashey, PhD – Thoughts on Science, Learning & Nutrition Practice
#261: Ari Snaevarsson – Eating Disorder Recovery, Body Positivity & Intuitive Eating
#260: Steve Taylor, RD - Sustainable Results, Human Behaviour & Dietary Approaches
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SNR #257: Andrew Jagim, PhD – Pre-Workout Supplementation: Current Evidence & Recommendations
SNR #256: Alex Leaf – Risks of High-Protein Diets?: Longevity, Gut Health & Microbiota
SNR #255: Alan Flanagan – Public Health Nutrition & the Role of Epidemiology
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