Opioid-use disorder (OUD), a risk factor and major contributor to opioid-related deaths, is often underdiagnosed and undertreated. Currently there are three FDA-approved pharmacologic treatments for OUD maintenance therapy: methadone, buprenorphine (with or without naloxone), and naltrexone. Despite definitive evidence that methadone and buprenorphine products are effective in the treatment of OUD, there are still considerable accessibility and availability barriers that patients face when seeking Medication Assisted Treatment (MAT). The EXtended-release naltrexone vs Buprenorphine/naloxone for Opioid Treatment (X:BOT) trial compared the efficacy and safety of XR-NTX and BUP-NX to induce and maintain a patient with OUD on MAT as well as reducing opioid overdoses, relapses, and cravings.
Guest Author: Jordan L. Wulz, PharmD, MPH, BC-ADM, CHC
Music by Good Talk
Strategies for Managing Hypertension: Is the Paradigm Shifting?
Don’t Kid Yourself: Broad- versus Narrow-Spectrum Antibiotics in Children
Using Sotagliflozin In Tandem with Insulin: Weighing the Benefits in Type 1 Diabetes
Can We KEEP Perimenopausal Women Sexually Satisfied?
Know When to Hold 'Em - Know When to Fold 'Em. Deprescribing in BPH.
ARCH Study: Is Romosozumab better than Alendronate for the Fracture-Prone?
SPRINTing towards lower BP goals : A re-analysis of the ACCORD-BP trial
Therapy for Early-Stage COPD: What is the GOLDen Regimen?
Inflammatory Statements about Cardiovascular Risk Reduction: The CANTOS Trial
Top Ten Things Every Clinician Should Know About the 2017 Hypertension Guidelines
Where is the COMPASS Taking Us? Rivaroxaban, Aspirin, or Both for Stable CVD ?
Azithromycin to Prevent Asthma Exacerbations: What AMAZES Us and What Doesn’t
Painstaking Efforts to Improve Opioid Stewardship
Painting a New CANVAS for SGLT-2 Inhibitors?
Validating HERDOO2 - When is it Safe to Stop Therapy After an Unprovoked VTE?
Testing the Limits on Blood Glucose Monitoring: Can We Safely Cut Back?
Are Statins ALL THAT for Primary Prevention in Older Adults? A Second Look at ALLHAT-LLT
Wrapping up Knee Pain: Cabbage Leaf Wraps for Osteoarthritis of the Knee
All for One and FOURIER for All!
Create your
podcast in
minutes
It is Free
Good Nurse Bad Nurse
The Relaxback UK Show
On Call With Dr. Anselm Anyoha
The Doctor’s Farmacy with Mark Hyman, M.D.
The Peter Attia Drive