Haemolytic uraemic syndrome | why we shouldn't scatter-gun antibiotics for every case of diarrhoea

Haemolytic uraemic syndrome is one of the most common causes of acute renal failure in children. The classic triad of HUS includes haemolytic anaemia, low platelet count and acute kidney injury. It is most often triggered by recent gastroenteritis from Shiga-like toxin producing E. coli.

Management is largely supportive, focusing on managing hypertension, transfusion of blood products as required, and dialysis if needed. In this episode, we run through the pathophysiology, presentation, pertinent investigations, and everything else you need to know about HUS!

 

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(This isn’t individual medical advice, please use your own clinical judgement and local guidelines when caring for your patients)