August 2022: Subcortical Brain Development in Autism and Fragile X Syndrome

Dr. Mark D. Shen (University of North Carolina, Chapel Hill) discusses the trajectory of brain development in infants at risk for autism spectrum disorder (ASD) and fragile X syndrome.  Longitudinal imaging was captured from 6 to 24 months to see how brain development differed between groups, and the development of the amygdala in infants at risk for ASD prior to onset of social deficits and clinical diagnosis.

• Shen interview [01:03]
• Why look at patients with potential ASD diagnosis in conjunction with fragile X syndrome patients? [04:20]
• Why are differences in brain structure important? [05:46]
• What’s the advantage of earlier diagnosis of ASD? [08:16]
• What’s next for your research? [09:48]
• Kalin interview [11:47]
• Shen et al. [12:09]
• Girault et al. [15:30]
• Gerlach et al. [19:13]
• Mosholder et al. [22:12]
• Summary [25:31]

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