A controversial dam in the Amazon unites Indigenous people and scientists, and transplanting mitochondria to treat rare diseases

Keeping an eye on the largest hydroelectric project in the Amazon basin, and helping patients with deletions in their mitochondrial DNA

We are starting off the new year with producer Kevin McLean and freelance science journalist Sofia Moutinho. They discuss a controversial dam in the Brazilian Amazon and how Indigenous peoples and researchers are trying to monitor its impact.

Then, host Sarah Crespi speaks with Elad Jacoby, an expert in pediatric hematology and oncology at the Sheba Medical Center and Tel Aviv University, about the many wonders of mitochondria. In a recent Science Translational Medicine paper, his team took advantage of the fact that mitochondria are almost exclusively inherited from our mothers to transfer mothers’ mitochondria into their children as treatment for mitochondrial genome deletions.

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This week’s episode was produced with help from Podigy.

[Image: Dado Galdieri/Hilaea Media; Music: Jeffrey Cook]

[alt: two fishermen in a boat with podcast symbol overlay]

Authors: Sarah Crespi; Kevin McLean; Sofia Moutinho

Episode page: https://www.science.org/doi/10.1126/science.adg5434

About the Science Podcast: https://www.science.org/content/page/about-science-podcast 

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