On this episode, Jonathan is joined by Noel Morgan, Professor of Endocrine Pharmacology, University of Exeter, UK. The pair discuss Morgan’s extensive research in diabetes, including his research on islet biology and signalling mechanisms regulating pro-inflammatory and anti-inflammatory processes in β-cells in Type 1 diabetes. They further discuss areas of research that excite and frustrate him, how we can change beliefs and behaviours associated with diabetes, and the future of diabetes research.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(02:00)-Morgan's origin story
(03:30)-Experiences from Nashville, USA
(06:00)-Islet biology
(08:00)-Insulin secretion control
(12:25)-Aetiology and differences between Type 1 and Type 2 diabetes
(15:10)-The largest collection of rare pancreas samples in the world
(17:50)-Different ‘types’ of Type 1 diabetes
(20:15)-Pro-insulin
(22:35)-To B or not to B?
(24:35)-Rituximab
(26:00)-Dorothy Hodgkin Lecture
(28:00)-The global obesity epidemic and changing behaviour
(31:45)-The war on obesity
(33:40)-A longer, unhealthy life?
(34:45)-Exciting topics and immunotherapy
(36:50)-Three wishes
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