MS Research: Using Epigenetic Clocks and Biomarkers to Assess Biological Aging

Guest: Yinan Zhang, MD

Chronological age is the biggest early driver of disease progression in patients with multiple sclerosis (MS). That’s why a team of researchers wanted to explore whether biomarkers like p16 and the epigenetic clock can be used to assess biological aging in patients with MS. They found that while patients with MS are aging faster than people without MS based on the epigenetic clock biomarker, no chronological age correlation in p16 expression has been identified in patients with MS. Dive further into these findings with Dr. Yinan Zhang, an Assistant Professor of Neurology at Ohio State University who presented this research at the 2024 ACTRIMS Forum.