BioTechniques Digital and Assistant Editors Abigail Sawyer and Tristan Free talk to Theo Roth from the University of California San Francisco Marsen Lab (USA). Having recently made headlines for his work in T-cell engineering, Theo takes us through his groundbreaking CRISPR research, its potential impacts in CAR-T cell therapy and further afield, whilst also tackling the evolving ethics in gene editing and the potential benefits of using ssDNA over dsDNA for CRISPR techniques.
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