Game Changers Documentary, Living Past 110 Years, and Cardio's impact on Mortality

In this episode, we dive into a question related to the latest Game Changers controversy, what lets people live to be over 110 years old, and the impact of cardio/long distance exercise on mortality.

Game Changers: 1:58
Supercentenarians: 13:25
Cardio on Mortality: 19:06

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References
Supercentenarians:
Kosuke Hashimoto, Tsukasa Kouno, Tomokatsu Ikawa, Norihito Hayatsu, Yurina Miyajima, Haruka Yabukami, Tommy Terooatea, Takashi Sasaki, Takahiro Suzuki, Matthew Valentine, Giovanni Pascarella, Yasushi Okazaki, Harukazu Suzuki, Jay W. Shin, Aki Minoda, Ichiro Taniuchi, Hideyuki Okano, Yasumichi Arai, Nobuyoshi Hirose, Piero Carninci. Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians. Proceedings of the National Academy of Sciences, 2019; 201907883 DOI: 10.1073/pnas.1907883116

Cardio on Mortality:
Zeljko Pedisic, Nipun Shrestha, Stephanie Kovalchik, Emmanuel Stamatakis, Nucharapon Liangruenrom, Jozo Grgic, Sylvia Titze, Stuart JH Biddle, Adrian E Bauman, Pekka Oja. Is running associated with a lower risk of all-cause, cardiovascular and cancer mortality, and is the more the better? A systematic review and meta-analysis. British Journal of Sports Medicine, 2019; bjsports-2018-100493 DOI: 10.1136/bjsports-2018-100493