Episode 90: Mild Cognitive Impairment (MCI) : 3 words you never want to hear.

Most of us have some idea what dementia is. Though we toss the word 

‘demented’ around as a put down, Dementia, and Alzheimers experienced up close is difficult to witness. In part why it is so difficult to watch others go through the decline is because much of it can be avoided entirely by adopting a Low Carb High Fat Ketogenic diet. If there was one specific condition that is most improved by ketones, this would be it. In fact, unlike other conditions that can be improved by a ketogenic diet, taking ketones directly for Alzheimers or dementia has become a gold mind for certain companies that are now in business of creating them. The market for both LCHF Ketogenic diet and for ketones is based on two truths, the rate of Alzheimers is at an all time high and will just increase, and Mild Cognitive Impairment is happening at a younger and younger age. Both demographics can be addressed fairly easily. Listen in to hear how we do that.
Sweethearts Forever. Then Came Alzheimer’s, Murder and Suicide.“They were absolutely soul mates.” 12-30-2019
https://www.nytimes.com/2019/12/29/nyregion/alzheimers-murder-suicide.html?te=1&nl=morning-briefing&emc=edit_NN_p_20191230§ion=longRead?campaign_id=9&instance_id=14852&segment_id=19935&user_id=8bf2db4cafbf95d4ce39e46957ce6942®i_id=73838898ion=longRead#commentsContainerDr.
Stephen Cunnane - April 26, 2018
https://www.youtube.com/watch?v=uiEY4wligpc&feature=youtu.be
Dr. Cunnane 2016-7Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937039/
conclusion:Ketones are the brain’s main alternative fuel to glucose and brain ketone uptake is still normal in MCI and in early AD, which would help explain why ketogenic interventions improve some cognitive outcomes in MCI and AD. We suggest that the brain energy deficit needs to be overcome in order to successfully develop more effective therapeutics for AD. At present, oral ketogenic supplements are the most promising means of achieving this goal.
A ketogenic drink improves brain energy and some measures of cognition in mild cognitive impairment https://www.researchgate.net/publication/332575159_A_ketogenic_drink_improves_brain_energy_and_some_measures_of_cognition_in_mild_cognitive_impairment
Emulsification Increases the Acute Ketogenic Effect and Bioavailability of Medium-Chain Triglycerides in Humans: Protein, Carbohydrate, and Fat Metabolism. 7-2017
https://www.ncbi.nlm.nih.gov/pubmed/29955713
Conclusions: Emulsification increased the ketogenic effect and decreased side effects in a dose-dependent manner for single doses of MCTs ≤30 g under matching conditions. Further investigation is needed to establish whether emulsification could sustain ketogenesis and minimize side effects and therefore be used as a treatment to change brain ketone availability over a prolonged period of time. 

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