2007 Infectious Diseases Society of America/American Thoracic Society Criteria for Defining Severe Community-acquired Pneumonia
Validated definition includes either one major criterion or three or more minor criteria
Minor criteria
Respiratory rate > 30 breaths/min PaO2/FIO2 ratio
Uremia (blood urea nitrogen level > 20 mg/dl)
Leukopenia* (white blood cell count , 4,000 cells/ml)
Thrombocytopenia (platelet count , 100,000/ml)
Hypothermia (core temperature , 368 C) Hypotension requiring aggressive fluid
resuscitation
Major criteria
Septic shock with need for vasopressors
Respiratory failure requiring mechanical ventilation
A special thanks to our Infectious Diseases Editor:
Angelica Cifuentes Kottkamp, MD
Infectious Diseases & Immunology
NYU School of Medicine