#28: loratadine (Claritin) | Treating Allergic Rhinitis, Conjunctivitis, and Urticaria

Loratadine is available over the counter and by prescription. Over the counter the most commonly known brand name is Claritin. Loratadine is a second generation antihistamine that works by antagonizing the H1 receptor. The main indications are for allergic rhinitis, conjunctivitis, and urticaria. There are many different dosage forms available from capsule, solution, syrup, tablet, chewable tablet, and disintegrating tablet. When dosing for adults the most common dosing is 10 mg po qd or 5 mg po bid with a max of 10 mg per day. For children 2-6 the chewable tablet or liquid is generally the preferred dosage form and dosed at 5 mg po qd (or 5 mL po qd if solution or syrup). When searching for an antihistamine safe during pregnancy second generation antihistamines are generally considered safe and preferred at the lowest effect dose. Limited side effects but sedation and drowsiness can occur.

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