Ep. 67: Endotoxin and PUFA As Primary Causes of Fatty Liver Disease (NAFLD Part 5)

In this episode we discuss:

• How endotoxin drives inflammation and stress while downregulating our metabolism

• Why alcoholic fatty liver disease isn’t all that different from non-alcoholic fatty liver disease

• The protective effects of saturated fats in NAFLD

• How endotoxin and polyunsaturated fats can cause NAFLD

• Nutrient deficiencies that contribute to energy failure and NAFLD

 

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Click here to check out the show notes: https://jayfeldmanwellness.com/ep-67-endotoxin-and-pufa-as-primary-causes-of-fatty-liver-disease-nafld-part-5/ 

 

Timestamps:

3:57 – the role of endotoxin in NAFLD

23:43 – how endotoxin drives inflammation and stress while downregulating our metabolism

30:35 – research looking at endotoxin as the cause of NAFLD

38:30 – how endotoxin mediates alcoholic liver disease and the protective effects of saturated fats 

44:56 – endotoxin and other damaging factors in the larger context of NAFLD

52:52 – the role of PUFA in NAFLD

1:12:05 – the contrasting effects of saturated fats and PUFA in alcohol-induced liver damage

1:24:22 – how nutrient deficiencies can cause energy failure and drive NAFLD

1:34:57 – how alcohol causes fatty liver and why alcoholic liver disease doesn’t vary considerably from NAFLD

1:38:49 – other factors that contribute to energy failure and drive NAFLD, including psychological stress, fasting, low-carb diets, low-calorie diets, excessive exercise protective effects of saturated fats