This Week In Wellness research out of Florida State University College of Medicine has linked the popular artificial sweetener Aspartame to anxiety in mice. In fact not only did it produce anxiety in the mice that consumed it, it also extended to their offspring for 2 generations.
https://www.sciencedaily.com/releases/2022/12/221208174226.htm
https://www.pnas.org/doi/10.1073/pnas.2213120119
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