Urgent Bite 155 - CYP3A4 interactions with statins

A drug interaction that should be at the front of our minds. 

 

Check out the Medsafe Data sheet here.

https://www.medsafe.govt.nz/profs/PUArticles/March2014StatinsAndCYPInteractions.htm

 

Check out this paper on a case of rhabdomyolysis. 

Fallah, A., Deep, M., Smallwood, D., & Hughes, P. (2013). Life-threatening rhabdomyolysis following the interaction of two commonly prescribed medications. The Australasian Medical Journal, 6(3), 112-114. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626026/#!po=83.3333

 

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