JNP Micro Podcast: Switching Neuron Contributions to Second Network

In this episode, coauthor Savanna-Rae H. Fahoum dives into her recent research, shedding light on "Switching Neuron Contributions to Second Network Activity" and "Neuropeptide Modulation of Bidirectional Internetwork Synapses." Collaborating with Dawn M. Blitz, they utilize rhythmic neuronal networks in crabs as a model to explore the complex interactions between these networks and neurons capable of switching their network participation. Their findings reveal that when a neuron transitions into dual-network activity, only the second network influences its activity within that context. Furthermore, while the switching neuron can effectively coordinate second network neurons and regulate their activity levels, it's not always indispensable, suggesting a nuanced regulation of switching neurons that challenges the traditional view of them merely as followers in additional networks.

 

Switching neuron contributions to second network activity

Savanna-Rae H. Fahoum and Dawn M. Blitz

Journal of Neurophysiology 2024 131:2, 417-434

 

https://doi.org/10.1152/jn.00149.2024