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About This Episode:
Losing at least 5% of one’s initial body weight is associated with improvements in glycaemic control, blood pressure, triglyceride levels, and other positive outcomes. Due to these reasons, it is typically recommended that individuals classified as overweight or obese should engage in effective weight loss interventions.
However, despite the potential for clinically significant weight loss through these interventions, weight regain is a common occurrence. This can be attributed to a combination of low adherence to weight control strategies and compensatory physiological mechanisms that influence weight regain.
Consequently, this may result in a cycle of losing and regaining weight over the long term, which is commonly referred to as “weight cycling.”
There are concerns regarding the potential harm to health and increased risk of chronic diseases associated with weight cycling. Some mechanisms have been proposed, such as the loss of lean mass during weight loss periods that is not regained when weight is regained. However, the evidence supporting the harmful effects of weight cycling on health is incomplete and many unanswered questions remain.
In this episode, we will examine the evidence published to date and draw evidence-based conclusions regarding the impact of weight cycling on long-term health.
#495: Circadian Clocks in Muscle & Exercise as a Time Cue – Prof. Karyn Esser
#494: Multiple Risk Factor Intervention Trial
#493: The Keys Equation – How Dietary Fats Impact Blood Cholesterol
SNP20: The Cumulative Exposure Model of LDL-C & Heart Disease
#491: Do High Protein Intakes Cause Insulin Resistance?
#490: How Does Exercise Impact Beta-cell Function in Type 2 Diabetes? – Mark Lyngbæk, MD
What is a Causal Risk Factor? (AMA with Alan)
#489: Inequalities in Diabetes Outcomes for African & Caribbean Communities – Prof. Louise Goff
#488: Does Time of Day Impact Hunger, Appetite & Satiety?
#487: Weight Cutting in Combat Sports – Jordan Sullivan
#486: Blood Glucose Spikes: How High is Too High? – Mario Kratz, PhD & Nicola Guess, PhD
#485: Does Menopause Alter Appetite?
SNP18: What is a Healthy Low-Carb Diet?
#484: Is Metabolic Adaptation an Illusion? – Eric Trexler, PhD
#483: What are the Effects of Very High Fiber Intakes?
#482: Carbohydrate Quality & Health – Andrew Reynolds, PhD
Is Personalized Nutrition Superior to General Nutrition Advice? (SNP 17)
#481: Why Saturated Fat Really Does Impact Heart Disease Risk
#480: How Much Fiber Do We Need for Good Health? – Prof. Joanne Slavin
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