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About This Episode:
It has been clearly demonstrated that elevated LDL-cholesterol (LDL-C), or perhaps more specifically pro-atherogenic lipoproteins, is causal in atherosclerosis development in humans.
One crucial concept within this is that the risk relates not only to the magnitude of elevated LDL-C, but the duration of exposure. Thus, the role of LDL-C in driving atherosclerosis is referred to as a “cumulative, integrated exposure over the lifecourse”.
But, what exactly does this mean?
In this episode, Danny discusses the cumulative exposure model of LDL-C in atherosclerosis, the evidence supporting it, and the implications of this for the “debates” that get raised in relation to LDL-C (or apoB-containing lipoproteins) and heart disease.
Links:
SNR #160: Tools That Have Been Invaluable to My Life
SNR #159: Phil Graham - The Diabetic's Guide to Muscle, Fat Loss & Fitness
SNR #158: Alex Ritson - Adaptive Thermogenesis, Thrifty Genes & Hedonic Eating
SNR #157: Sigma Weight Cutting System
SNR #156: 7 Philosophical Lessons from the Podcast in 2016 (End of Year Review)
#155: Kimber Stanhope, PhD - Effects of Sugar Consumption on Body Composition, Lipid Regulation and Insulin Sensitivity
SNR #154 Jeff Rothschild, RD – Intermittent Fasting, Time-Restricted Feeding & Circadian Biology
SNR #153: Dan Garner - Hydration Status, Electrolytes & Athlete Lab Analysis
SNR #152: Lyle McDonald – Glycaemic Load, Trigger Foods & Physiology vs. Practical Implementation
SNR #151: Planning the 4 Phases of Combat Sport Nutrition
SNR #150: Are You Really a "Hard-Gainer"? - 5 Reasons For Not Gaining Weight
SNR 149: Mike Israetel, PhD - Evidence-Based Healthy Eating Principles
SNR #148: Roundtable with the Sigma Team! - Hosted by HPA
SNR 147: Jeff Rothschild, RD - Carbohydrate Periodization for Endurance Athletes and How the Menstrual Cycle Impacts Training
SNR #146: Is Sugar Addiction a Real Thing? (A Scientific View)
SNR #145: Ian Dunican, PhD - Sleep, Training Timing & Performance in Elite Athletes
SNR #144: Is Inflammation a Problem & Should I Use an Anti-Inflammatory Diet?
SNR #143: Keith Baar, PhD - Tendon Stiffness, Collagen Production & Gelatin for Performance & Injury
SNR #142: Gar Benn - Nutrition Troubleshooting, Diet Evaluations & Effective Programming
#141: Performance Nutrition for Fighters - Common Mistakes
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