Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.
A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115 “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021 A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity. A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066 “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021) “Looking Beyond DNA to See Cancer with New Clarity,” Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily. Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019). See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more) Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed] Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1
--- Support this podcast: https://podcasters.spotify.com/pod/show/scientificsense/supportProf. Bill Gibson, Professor of Economics at the University of Vermont.
Prof. Morton Schapiro, President of Northwestern University and Prof. Gary Morson, Professor of the Arts and Humanities at Northwestern
Prof. Stephanie Seguino, Professor of economics at the University of Vermont
Prof. Michael Roberts, Professor of Finance at the Wharton School of the University of Pennsylvania
Prof. David Gerdes, Professor of Physics at the University of Michigan
Prof. Sarkis Mazmanian, Professor of Microbiology at the California Institute of Technology
Prof. Michael Dickinson, Professor of Bioengineering and Aeronautics at the California Institute of Technology
Prof. Michael Dinerstein, Assistant Professor of Economics at the University of Chicago
Prof. Francisco Quintana, Professor of Neurology at the Harvard Medical School
Prof. Arturo Alvarez-Buylla, Professor, Neurological Surgery at UCSF.
Prof. Carol Gould, Professor of Philosophy at Florida Atlantic University
Prof. Su Guo, Professor of Bioengineering and Therapeutic Sciences at UCSF
Prof. Cecilia Lunardini, Professor of Physics at Arizona State University.
Prof. Howard Fields, Professor Emeritus, Neurology at UCSF
Prof. Itay Goldstein, Professor of Finance and Economics at the Wharton School of the University of Pennsylvania
Prof. Richard Lebed, Professor of Physics at Arizona State University.
Prof. Ryan Hickox, Professor of Astronomy at Dartmouth College
Prof. Maria Kazachenko, Assistant Professor of Astrophysical & Planetary Science at the University of Colorado, Boulder
Prof Erik Berglöf, Professor of economics at the London School of Economics.
Prof. Scott Baraban, Professor & Chair in Neuroscience Research, UCSF
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