Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.
A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115 “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021 A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity. A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066 “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021) “Looking Beyond DNA to See Cancer with New Clarity,” Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily. Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019). See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more) Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed] Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1
--- Support this podcast: https://podcasters.spotify.com/pod/show/scientificsense/supportProf. Bruce Partridge, Emeritus Professor of Astronomy at Haverford college
Prof. John Dowling, Research Professor of Neurosciences at Harvard
Prof. Raja GuhaThakurta, Professor of Astrophysics at the University of California Santa Cruz
Prof. Scott Gaudi, Professor of Astronomy at Ohio State University
Prof. James McGaugh, Emeritus Professor of Neurobiology at the University of California, Irvine
Prof. Daniel Holz, Professor of Astrophysics at the University of Chicago
Prof. Kent Berridge, Professor of Neuroscience at the University of Michigan
Prof. Ira Rothstein, Professor of Physics at Carnegie Mellon University
Prof. Doug Duncan is an emeritus faculty of Astrophysics at the University of Colorado
Prof. James Kasting, Professor of Atmospheric Science at Penn State University
Dr. Josh Winn, Physicist and astronomer at Princeton University.
Prof. Gordon Fishell, Professor of Neurobiology at Harvard Medical School
Prof. Marc Pinsonneault, Theorist on the evolution of stars at Ohio State University
Prof. Gregory Laughlin, Professor of Astrophysics at Yale University
Prof. Fran Bagenal, Professor of Astrophysics at the University of Colorado Boulder
Prof. Edwin Turner, Professor of Astrophysical Sciences at Princeton University
Dr. Chris Bleakley, Associate Professor of Computer Science at University College Dublin
Prof. Laith Abu-Raddad, Professor of Population Health at Cornell University in Qatar
Prof. Paul Turner, Professor of Ecology and Evolutionary Biology at Yale University.
Prof. Matthias Doepke, Research Professor of Economics at Northwestern University
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